Products Tildrakizumab was approved as an injectable in the United States and EU in 2018 and in many countries in 2019 (ilumetri). Structure and properties Tildrakizumab is a humanized IgG1/k monoclonal antibody with an approximate molecular mass of 147 kDa. It is produced by biotechnological methods. Effects Tildrakizumab (ATC L04AC17) has immunosuppressive and anti-inflammatory properties. … Tildrakizumab
Products Domperidone is commercially available as film-coated tablets, lingual tablets, and as a suspension (Motilium, generics). It was synthesized in 1974 and has been approved in many countries since 1979. Structure and properties Domperidone (C22H24ClN5O2, Mr = 425.9 g/mol) exists as a white powder that is practically insoluble in water. It is a benzimidazole derivative … Domperidone
Products Pitavastatin is commercially available in the form of film-coated tablets (Livazo). It was first approved in many countries in July 2012. In Japan, it has been on the market since 2003, and it is also available in other countries such as the United States and Germany. Structure and properties Pitavastatin (C25H24FNO4, Mr = 421.5 … Pitavastatin
Products Fenticonazole is no longer on the market in many countries (Mycodermil Crème, Gyno-Mycodermil, Crème). Structure and properties Fenticonazole (C24H20Cl2N2OS, Mr = 455.4 g/mol) is present in drugs as fenticonazole nitrate, a white crystalline powder that is practically insoluble in water. It is a racemate. Effects Fenticonazole (ATC D01AC12, ATC G01AF12) has antifungal properties; see … Fenticonazole
Products Pyrimethamine is commercially available in tablet form (Daraprim). The combination Fansidar (+ sulfadoxine) is off the market (malaria). Structure and properties Pyrimethamine (C12H13ClN4, Mr = 248.7 g/mol) is a diaminopyrimidine. It exists as a white crystalline powder or as colorless crystals and is practically insoluble in water. Effects Pyrimethamine (ATC P01BD01) has antiparasitic properties. … Pyrimethamine
Products Atazanavir is commercially available in capsule form (Reyataz). It has been approved in many countries since 2004. Generic versions were registered in 2017. Structure and properties Atazanavir (C38H52N6O7, Mr = 704.9 g/mol) is present in drugs as atazanavir sulfate, a white to slightly yellow crystalline powder that is sparingly soluble in water. Effects Atazanavir … Atazanavir
Products Clidinium bromide is commercially available in the form of dragées in combination with chlordiazepoxide (Librax). It has been approved in many countries since 1961. Structure and properties Clidinium bromide (C22H26BrNO3, Mr = 432.4 g/mol) Effects Clidinium bromide (ATC A03CA02) has anticholinergic and spasmolytic properties on smooth muscle. Indications In combination with chlordiazepoxide: Gastrointestinal or … Clidinium Bromide
Products Hypromellose is commercially available in tear substitutes in the form of eye drops. It is also present in tablets as a pharmaceutical [excipient>]. Structure and properties Hypromellose (methylhydroxypropyl cellulose) is a partially -methylated and -(2-hydroxypropylated) cellulose. It exists as a white, yellowish white or grayish white powder or as granules and is practically insoluble … Hypromellose (Hydroxypropylmethylcellulose)
Products Ibalizumab was approved in the United States in 2018 and in the EU in 2019 (Trogarzo, TaiMed Biologics). Structure and properties Ibalizumab is a humanized IgG4 monoclonal antibody. It is produced by biotechnological methods. Unlike most antiviral agents, it is directed against an endogenous drug target rather than the virus. Effects Ibalizumab has antiviral … Ibalizumab
Products Chlorambucil is commercially available in the form of film-coated tablets (Leukeran). It has been approved in many countries since 1957. Structure and properties Chlorambucil (C14H19Cl2NO2, Mr = 304.2 g/mol) is an aromatic nitrogen-lost derivative. It exists as a white crystalline powder that is practically insoluble in water. The effects are due to the active … Chlorambucil
Products Lutropin alfa is commercially available as an injectable (Luveris). It has been approved in many countries since 2002. Structure and properties Lutropin alfa is a is a recombinant human luteinizing hormone (LH). LH is a glycoprotein. Indications In combination with follicle-stimulating hormone (FSH) to stimulate follicular maturation in women with severe LH and FSH … Lutropin Alfa
Products In many countries, there are no drugs containing dehydrochlormethyltestosterone on the market. The active ingredient was lanicized in the 1960s and distributed by the state-owned VEB Jenapharm, based in Jena, Thuringia (Oral-Turinabol tablets). Structure and properties Dehydrochloromethyltestosterone (C20H27ClO2, Mr = 334.9 g/mol) is a chlorinated derivative of methyltestosterone. Effects Dehydrochloromethyltestosterone has anabolic and androgenic … Dehydrochloromethyltestosterone
