Citrulline

Products Citrulline is commercially available in the form of sachets containing a drinkable solution (Biostimol). It has been approved in many countries since 1996. Structure and properties L-(+)-citrulline (C6H13N3O3, Mr = 175.2 g/mol) exists as a white crystalline powder that is readily soluble in water. Citrulline is an amino acid found, for example, in watermelon. … Citrulline

Buformin

Products Buformin (Silubin retard, dragées) is no longer commercially available in many countries and many more because of the potential adverse effects. Structure and properties Buformin (C6H15N5, Mr = 157.2 g/mol) is a 1-butylbiguanide with a similar structure to metformin from the same drug group. It is present in drugs as buformin hydrochloride. Effects Buformin … Buformin

Cladribine

Products Cladribine was approved for the treatment of multiple sclerosis in the EU in 2017 and in the United States and many countries in 2019 in tablet form (Mavenclad). Cladribine has also been commercially available as an infusion and injection solution in many countries since 1998 (Litak). This article relates to MS therapy. Structure and … Cladribine

Bumetanide

Products Bumetanide was commercially available in tablet form (Burinex, off label). It was approved in many countries in 1974. Structure and properties Bumetanide (C17H20N2O5S, Mr = 364.4 g/mol) is a white crystalline powder that is practically insoluble in water. Effects Bumetanide (ATC C03CA02) is diuretic with rapid onset and short duration of action. Indications Oedema … Bumetanide

Clarithromycin

Products Clarithromycin is commercially available as film-coated tablets, sustained-release tablets, oral suspension, and powder for solution for infusion (Klacid, generics). It has been approved in many countries since 1990. Clarithromycin should not be confused with ciprofloxacin. Structure and properties Clarithromycin (C38H69NO13, Mr = 747.96 g/mol) exists as a white crystalline powder that is practically insoluble … Clarithromycin

Bunazosin

Products Bunazosin is commercially available in the form of sustained-release tablets (Andante). The drug is not registered in many countries. Structure and properties Bunazosin (C19H27N5O3, Mr = 373.4 g/mol) is present in drugs as bunazosin hydrochloride. It is a quinazoline derivative. Effects Bunazosin (ATC C02CA) is antihypertensive. Its effects are due to selective and competitive … Bunazosin

Clascoteron

Products Clascoterone was approved as a cream in the United States in 2020 (Winlevi). Structure and properties Clascoterone (C24H34O5, Mr = 402.5 g/mol) corresponds to the steroid cortexolone-17α-propionate. It exists as a white powder that is practically insoluble in water. Effects Clascoterone has antiandrogenic properties. The effects are due to antagonism at androgen receptors. Androgens … Clascoteron

Medications: Types and Dosage Forms

The doctor prescribes them, the pharmacist sells them: Medicines. Medicines are drugs intended to cure a disease as well as to prevent or diagnose a disease. Medicines have long been made from plants, plant parts, animal and chemical compounds. In the meantime, pharmacologists are increasingly focusing their attention on genetic engineering and synthetic manufacturing processes. … Medications: Types and Dosage Forms

Medications: Storage and Shelf Life

Medicines should be stored in a cool, dark and dry place, preferably in a cabinet. Shoe boxes, tin cans with or without lids, or just any drawer are unsuitable. The best place for a medicine cabinet is the bedroom or an unheated adjoining room. Bathrooms and kitchens are usually too humid and too warm – … Medications: Storage and Shelf Life

Strawberry: Healthy Ingredients

Strawberry time! The red deliciousness laughs again from market stalls and plantations and offers one of the healthiest pleasures of the summer. Most people can’t get enough of strawberries, and they don’t have to: strawberries are 90 percent water, and with their amazingly low nutritional value of 32 kilocalories per 100 grams, they provide vitamins … Strawberry: Healthy Ingredients