Products Cladribine was approved for the treatment of multiple sclerosis in the EU in 2017 and in the United States and many countries in 2019 in tablet form (Mavenclad). Cladribine has also been commercially available as an infusion and injection solution in many countries since 1998 (Litak). This article relates to MS therapy. Structure and … Cladribine
Products Bumetanide was commercially available in tablet form (Burinex, off label). It was approved in many countries in 1974. Structure and properties Bumetanide (C17H20N2O5S, Mr = 364.4 g/mol) is a white crystalline powder that is practically insoluble in water. Effects Bumetanide (ATC C03CA02) is diuretic with rapid onset and short duration of action. Indications Oedema … Bumetanide
Products Clarithromycin is commercially available as film-coated tablets, sustained-release tablets, oral suspension, and powder for solution for infusion (Klacid, generics). It has been approved in many countries since 1990. Clarithromycin should not be confused with ciprofloxacin. Structure and properties Clarithromycin (C38H69NO13, Mr = 747.96 g/mol) exists as a white crystalline powder that is practically insoluble … Clarithromycin
Products Bunazosin is commercially available in the form of sustained-release tablets (Andante). The drug is not registered in many countries. Structure and properties Bunazosin (C19H27N5O3, Mr = 373.4 g/mol) is present in drugs as bunazosin hydrochloride. It is a quinazoline derivative. Effects Bunazosin (ATC C02CA) is antihypertensive. Its effects are due to selective and competitive … Bunazosin
Products Clascoterone was approved as a cream in the United States in 2020 (Winlevi). Structure and properties Clascoterone (C24H34O5, Mr = 402.5 g/mol) corresponds to the steroid cortexolone-17α-propionate. It exists as a white powder that is practically insoluble in water. Effects Clascoterone has antiandrogenic properties. The effects are due to antagonism at androgen receptors. Androgens … Clascoteron
Products Buphenin was included in Arbid drops in combination with diphenylpyralin until late 2011. Structure and properties Buphenin (C19H25NO2, Mr = 299.41 g/mol), like other sympathomimetics, has structural similarity to catecholamines, for example, epinephrine. Effects Buphenine (ATC C04AA02) is β-sympathomimetic and thus vasodilatory and positively inotropic. Indications No longer commercially available in many countries for … Buphenin
Products Clavulanic acid is sold exclusively in combinations with antibiotic amoxicillin. In addition to the original Augmentin, numerous generics are also available. Structure and properties Clavulanic acid (C8H9NO5, Mr = 199.16 g/mol) is present in drugs as potassium clavulanate, the potassium salt of clavulanic acid. Potassium clavulanate is a white, crystalline, hygroscopic powder that is … Clavulanic Acid
Introduction Diaphragmatic breathing or synonymously also called “abdominal breathing” is one of two ways of breathing besides chest breathing. Medically, it is not correct to equate diaphragmatic breathing with abdominal breathing, but both terms are used in the same sense. Breathing with the diaphragm is an automatic, unconscious process. You do not have to think … The diaphragmatic breathing
Diaphragmatic breathing exercises To breathe more consciously with the diaphragm there are some exercises. If possible, find a quiet place to consciously perceive the diaphragmatic breathing. Exercise 1: Lie down flat on the floor or sit upright on a chair, put your hand on your stomach and breathe deeply into your stomach so that you … Diaphragmatic breathing exercises | The diaphragmatic breathing
Hiccups Hiccups are caused by a sudden cramping of the diaphragm, whereby the glottis between the vocal folds is reflexively closed. When the air already inhaled hits the closed glottis, the typical “hiccup” occurs. The cause of the diaphragm‘s cramping is an irritation of the phrenic nerve. This is the nerve that innervates the diaphragm. … Hiccups | The diaphragmatic breathing
